BODIPY-C12 Ceramide (d18:1/12:0)

BODIPY-C12 Ceramide (B12Cer) is a fluorescently tagged form of C12 ceramide (Cay-22530) that displays excitation/emission maxima of 505/540 nm, respectively. It is formed when acid sphingomyelinase hydrolyzes BODIPY-C12 sphingomyelin in vitro and has been used to quantify acid sphingomyelinase activity in plasma from patients with Niemann-Pick disease.Formal Name: (T-4)-[lambda-(3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-3,5-dimethyl-1H-pyrrole-2-dodecanamidato-kappaN1]difluoro-boron. CAS Number: 1246355-58-7. Synonyms: BODIPY-C12 Ceramide, BODIPY-Ceramide (d18:1/12:0), BODIPY-Cer(d18:1/12:0), BODIPY-N-Lauroyl-D-erythro-Sphingosine, B12Cer. Molecular Formula: C42H70BF2N3O3. Formula Weight: 713.8. Purity: >98%. Emission: 540 nm. Excitation: 505 nm. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: [F][B-]([N]1C2=C(C)C=C1C)([N+](C(C(C)=C3)=C2CCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO)=O)=C3C)[F]. InChi Code: InChI=1S/C42H70BF2N3O3/c1-6-7-8-9-10-11-12-13-14-15-19-22-25-28-39(50)38(32-49)46-40(51)29-26-23-20-17-16-18-21-24-27-37-41-33(2)30-35(4)47(41)43(44,45)48-36(5)31-34(3)42(37)48/h25,28,30-31,38-39,49-50H,6-24,26-27,29,32H2,1-5H3,(H,46,51)/b28-25+/t38-,39+/m0/s1. InChi Key: NGWZKZIJSBUOIZ-BOOOSZIVSA-N.