beta-Muricholic Acid

beta-Muricholic acid (beta-MCA) is a murine-specific primary bile acid. Dietary administration of beta-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of beta-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.Formal Name: (5beta)-3alpha,6beta,7beta-trihydroxy-cholan-24-oic acid. CAS Number: 2393-59-1. Synonyms: 5beta-Cholanic Acid-3alpha,6beta,7beta-triol, beta-MCA. Molecular Formula: C24H40O5. Formula Weight: 408.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. SMILES: OC(CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O. InChi Code: InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21+,22-,23-,24-/m1/s1. InChi Key: DKPMWHFRUGMUKF-CRKPLTDNSA-N.