beta-Estradiol 17-valerate

beta-Estradiol 17-valerate is a synthetic estrogen. It increases estrogen receptor beta (ERbeta), but not ERalpha, levels in the hippocampus and cortex of ovariectomized rats when administered at a dose of 0.3 mg/day. Intradermal administration of beta-estradiol 17-valerate (5 µg/animal) induces transient permanent diestrus and decreases litter size in rats. beta-Estradiol 17-valerate has been used to induce polycystic ovarian syndrome in rats. It has been found in wastewater effluent. Formulations containing beta-estradiol 17-valerate have been used in hormone replacement therapy and in the treatment of menopausal symptoms, as well as in oral contraceptives in combination with dienogest.Formal Name: (17beta)-estra-1,3,5(10)-triene-3,17-diol, 17-pentanoate. CAS Number: 979-32-8. Synonyms: Estradiol 17beta-valerate, NSC 17590. Molecular Formula: C23H32O3. Formula Weight: 356.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 2 mg/ml. lambdamax: 282 nm. SMILES: C[C@@]12[C@](CC[C@@H]2OC(CCCC)=O)([H])[C@]([C@]3([H])CC1)([H])CCC4=C3C=CC(O)=C4. InChi Code: InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/m1/s1. InChi Key: RSEPBGGWRJCQGY-RBRWEJTLSA-N.