beta-acetyl-Boswellic Acid

Boswellic acids are pentacyclic triterpenes first isolated from the resin of Boswellia plants. They have anti-inflammatory and anti-arthritic actions in mice. beta-acetyl-Boswellic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) that shows selectivity for 5-LO over 12-LO or COX. When studied as a 1:1 mixture with alpha-acetyl-boswellic acid, it inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells.Formal Name: (3alpha,4beta)-3-(acetyloxy)-urs-12-en-23-oic acid. CAS Number: 5968-70-7. Synonyms: ABA, 3-O-acetyl-beta-Boswellic acid, beta-Boswellic acid acetate. Molecular Formula: C32H50O4. Formula Weight: 498.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml, Ethanol: 5 mg/ml. SMILES: C[C@]1(C(O)=O)[C@H](OC(C)=O)CC[C@]2(C)[C@@]3([H])CC=C4[C@](CC[C@]5(C)[C@@]4([H])[C@@H](C)[C@H](C)CC5)(C)[C@]3(C)CC[C@]21[H]. InChi Code: InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32?/m1/s1. InChi Key: YJBVHJIKNLBFDX-MWEIDVNDSA-N. Origin: Plant/Boswelli aserrata.