Arachidonoyl Ethanolamide-d8

Arachidonoyl ethanolamide-d8 (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is an endogenous cannabinoid neurotransmitter that binds to both CB1 and CB2 receptors. AEA inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM, compared to 46 nM for Delta9-THC.Formal Name: N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide-5,6,8,9,11,12,14,15-d8. CAS Number: 924894-98-4. Synonyms: AEA-d8, Anandamide-d8. Molecular Formula: C22H29D8NO2. Formula Weight: 355.6. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 1 mg/ml EtOH:PBS pH 7.2: can dilute 1:1.6 (>380 µg/ml), 10 mg/ml EtOH:PBS pH 7.2: can dilute 1:1 (>5 mg/ml) (fro, 100 ¿g/ml EtOH:PBS pH 7.2: can dilute 1:1.6 (>38 µg/ml) (, DMF: >10 mg/ml (from AEA), DMSO: >30 mg/ml (from AEA), Ethanol: >100 mg/ml (from AEA), PBS pH 7.2: <100 µg/ml (from AEA). SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO. InChi Code: InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-/i6D,7D,9D,10D,12D,13D,15D,16D. InChi Key: LGEQQWMQCRIYKG-FBFLGLDDSA-N.