Arachidonic Acid-d8

Arachidonic acid-d8 is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid. CAS Number: 69254-37-1. Synonyms: AA-d8, FA 20:4-d8. Molecular Formula: C20H24D8O2. Formula Weight: 312.5. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 0.1 M Na2CO3: 1.7 mg/ml, DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: Miscible. SMILES: CCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O. InChi Code: InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i6D,7D,9D,10D,12D,13D,15D,16D. InChi Key: YZXBAPSDXZZRGB-FBFLGLDDSA-N. Side Chain Carbon Sum: 20:4.