Antrodin A

Antrodin A
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay36094-1 1 mg -

6 - 10 Werktage*

67,00 €
Cay36094-5 5 mg -

6 - 10 Werktage*

302,00 €
Cay36094-10 10 mg -

6 - 10 Werktage*

469,00 €
Cay36094-25 25 mg -

6 - 10 Werktage*

671,00 €
 
Antrodin A is a microbial metabolite originally found in A. camphorata that has antiviral and... mehr
Produktinformationen "Antrodin A"
Antrodin A is a microbial metabolite originally found in A. camphorata that has antiviral and hepatoprotective activities. It is an inhibitor of hepatitis C virus (HCV) protease (IC50 = 0.9 µg/ml). Antrodin A reduces cytotoxicity in Vero cells infected with herpes simplex virus 1 (HSV-1) or HSV-2 (IC50s = 5.8 and 5.5 µg/ml, respectively) and has additive effects on HSV-induced cytotoxicity when combined with the antiviral guanosine analog acyclovir (Cay-14160). It decreases viral plaque formation in Vero cells infected with HSV-1 or HSV-2 in a concentration-dependent manner. Antrodin A (200 mg/kg per day) inhibits alcohol-induced increases in serum triglyceride levels and decreases in serum HDL levels in a mouse model of alcoholic fatty liver disease (ALD). It also prevents alcohol-induced increases in hepatic lipid accumulation and the activity of serum alanine transaminase (ALT) and aspartate aminotransferase (AST), as well as decreases in the activity of malondialdehyde (MDA), superoxide dismutase (SOD), and catalase and in the levels of glutathione (GSH) in isolated mouse liver in the same model.Formal Name: 3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-4-(2-methylpropyl)-2,5-furandione. CAS Number: 656830-24-9. Synonyms: Camphorataanhydride A. Molecular Formula: C19H22O4. Formula Weight: 314.4. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Acetonitrile: Soluble, DMSO: Soluble, Ethanol: Soluble. SMILES: C/C(C)=C/COC1=CC=C(C=C1)C(C(O2)=O)=C(CC(C)C)C2=O. InChi Code: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9,13H,10-11H2,1-4H3. InChi Key: ZXIUCXGVUOQMSH-UHFFFAOYSA-N. Origin: Synthetic.
Schlagworte: Camphorataanhydride A, 3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-4-(2-methylpropyl)-2,5-furandione
Hersteller: Cayman Chemical
Hersteller-Nr: 36094

Eigenschaften

Anwendung: Microbial metabolite, antiviral / hepatoprotective agent
MW: 314.4 D
Formel: C19H22O4
Reinheit: >95%
Format: Solution

Datenbank Information

CAS : 656830-24-9| Passende Produkte
KEGG ID : K22273 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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