9322-O16B

9322-O16B is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing 9322-O16B and encapsulating mRNA encoding chimeric antigen receptors (CARs) have been used in the generation of anti-CD19 CAR macrophages with anticancer activity.Formal Name: bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(2-methyl-1H-imidazol-1-yl)propyl)azanediyl)dipropionate. CAS Number: 2909427-23-0. Molecular Formula: C41H77N3O4S4. Formula Weight: 804.3. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Chloroform: Soluble, Ethanol: Soluble. SMILES: O=C(CCN(CCC(OCCSSCCCCCCCCCCCC)=O)CCCN1C=CN=C1C)OCCSSCCCCCCCCCCCC. InChi Code: InChI=1S/C41H77N3O4S4/c1-4-6-8-10-12-14-16-18-20-22-35-49-51-37-33-47-40(45)25-30-43(28-24-29-44-32-27-42-39(44)3)31-26-41(46)48-34-38-52-50-36-23-21-19-17-15-13-11-9-7-5-2/h27,32H,4-26,28-31,33-38H2,1-3H3. InChi Key: RNUDNMKQWDJFAS-UHFFFAOYSA-N.