4beta-hydroxy Cholesterol-d7

4beta-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 4beta-hydroxy cholesterol (Cay-19518) by GC- or LC-MS. 4beta-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation. It is formed from cholesterol by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5. 4beta-hydroxy Cholesterol has an unusually long half-life in plasma (~60 hours) as a result of slow elimination, particularly due to a slow rate of 7alpha-hydroxylation, which is the rate-limiting step for further conversion into bile acids.Formal Name: cholest-5-ene-25,26,26,26,27,27,27-d7-3beta,4beta-diol. CAS Number: 1246302-80-6. Molecular Formula: C27H39D7O2. Formula Weight: 409.7. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble. SMILES: O[C@H]([C@@H]1O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C. InChi Code: InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3/t18-,19+,20-,21+,22+,24+,25-,26-,27-/m1/s1/i1D3,2D3,17D. InChi Key: CZDKQKOAHAICSF-BZNWTYAPSA-N.