4-hydroxy Tolbutamide

4-hydroxy Tolbutamide is a metabolite of the potassium channel antagonist tolbutamide (Cay-19888). It is formed from tolbutamide by the cytochrome P450 (CYP) isoform CYP2C9 in human liver microsomes and COS-7 cell lysates expressing the human enzyme. 4-hydroxy Tolbutamide has been used as a marker of CYP2C9 activity in rat hepatocytes.Formal Name: N-[(butylamino)carbonyl]-4-(hydroxymethyl)-benzenesulfonamide. CAS Number: 5719-85-7. Molecular Formula: C12H18N2O4S. Formula Weight: 286.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. lambdamax: 229 nm. SMILES: CCCCNC(=O)NS(=O)(=O)c1ccc(CO)cc1. InChi Code: InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16). InChi Key: SJRHYONYKZIRPM-UHFFFAOYSA-N.