3,4-Dihydroxyphenyl ethanol

3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12- and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 µM, respectively. It does not inhibit, and may actually enhance, COX activity. 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis.Formal Name: 4-(2-hydroxyethyl)-1,2-benzenediol. CAS Number: 10597-60-1. Synonyms: Ba2774, DOPET, 3-Hydroxytyrosol. Molecular Formula: C8H10O3. Formula Weight: 154.2. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Organic solvents: freely soluble (>50 mg/ml), PBS pH 7.2: >50 mg/ml. SMILES: OCCc1ccc(O)c(O)c1. InChi Code: InChI=1S/C8H10O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,9-11H,3-4H2. InChi Key: JUUBCHWRXWPFFH-UHFFFAOYSA-N. Origin: Synthetic.