2,3-dinor Thromboxane B2

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 2,3-dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker for in vivo TXA2 synthesis. In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).Formal Name: 9alpha,11,15S-trihydroxy-2,3-dinor-thromba-5Z,13E-dien-1-oic acid. CAS Number: 63250-09-9. Synonyms: 2,3-dinor TXB2. Molecular Formula: C18H30O6. Formula Weight: 342.4. Purity: >95%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml (from TXB2), DMSO: 25 mg/ml (from TXB2), Ethanol: 100 mg/ml (from TXB2), PBS pH 7.2: 100 mg/ml (from TXB2). SMILES: O[C@@H]1[C@H](C/C=C\CC(O)=O)[C@@H](/C=C/[C@H](O)CCCCC)OC(O)C1. InChi Code: InChI=1S/C18H30O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h5-6,10-11,13-16,18-20,23H,2-4,7-9,12H2,1H3,(H,21,22)/b6-5-,11-10+/t13-,14-,15-,16+,18?/m0/s1. InChi Key: RJHNVFKNIJQTQF-LMIBIYGPSA-N.