17-trifluoromethylphenyl trinor Prostaglandin F2alpha isopropyl ester

Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2alpha is an analog of PGF2alpha that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2alpha isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2alpha. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.Formal Name: 9alpha,11alpha,15S-trihydroxy-17-trifluoromethyl-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester. Synonyms: 17-trifluoromethylphenyl trinor PGF2alpha isopropyl ester. Molecular Formula: C27H37F3O5. Formula Weight: 498.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS(pH 7.2) (1:5): 0.2 mg/ml. SMILES: O[C@@H](CCC1=CC=CC(C(F)(F)F)=C1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(OC(C)C)=O. InChi Code: InChI=1S/C27H37F3O5/c1-18(2)35-26(34)11-6-4-3-5-10-22-23(25(33)17-24(22)32)15-14-21(31)13-12-19-8-7-9-20(16-19)27(28,29)30/h3,5,7-9,14-16,18,21-25,31-33H,4,6,10-13,17H2,1-2H3/b5-3-,15-14+/t21-,22+,23+,24-,25+/m0/s1. InChi Key: SLQVIHUQICCVQY-KEQMOKKCSA-N.