17-trifluoromethylphenyl trinor Prostaglandin F2alpha ethyl amide

Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2alpha (17-trifluoromethylphenyl trinor PGF2alpha) is an analog of PGF2alpha that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2alpha ethyl amide is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2alpha. Ethyl amides of PGs can serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.Formal Name: 9alpha,11alpha,15S-trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, ethyl amide. CAS Number: 1621369-73-0. Synonyms: 17-trifluoromethylphenyl trinor PGF2alpha ethyl amide. Molecular Formula: C26H36F3NO4. Formula Weight: 483.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 25 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .15 mg/ml. SMILES: O[C@@H](CCC1=CC=CC(C(F)(F)F)=C1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(NCC)=O. InChi Code: InChI=1S/C26H36F3NO4/c1-2-30-25(34)11-6-4-3-5-10-21-22(24(33)17-23(21)32)15-14-20(31)13-12-18-8-7-9-19(16-18)26(27,28)29/h3,5,7-9,14-16,20-24,31-33H,2,4,6,10-13,17H2,1H3,(H,30,34)/b5-3-,15-14+/t20-,21+,22+,23-,24+/m0/s1. InChi Key: QLKKMIWGFNMQJQ-JZFYYOKZSA-N.