(±)11-HETE-d8

(±)11-HETE-d8 is intended for use as an internal standard for the quantification of 11-HETE by GC- or LC-MS. (±)11-HETE is formed non-enzymatically from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 11(R)-HETE is formed from arachidonic acid by COX-1, COX-2, and aspirin-acetylated COX-2. 11(R)- and 11(S)-HETE are formed from arachidonic acid via cytochrome P450 (CYP), with 11(R)-HETE formed at a higher ratio than 11(S)-HETE.Formal Name: (±)11-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid. Synonyms: (±)11-Hydroxyeicosatetraenoic Acid-d8. Molecular Formula: C20H24D8O3. Formula Weight: 328.5. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in acetonitrile. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 234 nm. SMILES: OC(/C([2H])=C/C([2H])=C([2H])\CCCCC)([2H])C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O. InChi Code: InChI=1S/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/b9-6-,10-7-,14-11-,16-13+/i6D,7D,9D,10D,11D,14D,16D,19D. InChi Key: GCZRCCHPLVMMJE-HSABKICUSA-N.