1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HETE (Cay-34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Cay-11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE, Cay-25871) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.Formal Name: 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid, (1R)-2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester. CAS Number: 947381-58-0. Synonyms: 15(S)-HETE-SAPE, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine. Molecular Formula: C43H78NO9P. Formula Weight: 784.1. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 237 nm. SMILES: OP(OC[C@H](OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(OCCN)=O. InChi Code: InChI=1S/C43H78NO9P/c1-3-5-7-8-9-10-11-12-13-14-17-20-23-26-30-34-42(46)50-38-41(39-52-54(48,49)51-37-36-44)53-43(47)35-31-27-24-21-18-15-16-19-22-25-29-33-40(45)32-28-6-4-2/h15-16,21-22,24-25,29,33,40-41,45H,3-14,17-20,23,26-28,30-32,34-39,44H2,1-2H. InChi Key: ICSHQSNRXGUFHT-AQLFUWFLSA-N. Side Chain Carbon Sum: 38:4.