1-Docosahexaenoyl-rac-glycerol

1-Docosahexaenoyl-rac-glycerol is a monoacylglycerol that contains docosahexaenoic acid (DHA, Cay-90310, Cay-17950) at the sn-1 position. It reduces smooth muscle tension induced by endothelin-1 (ET-1) in isolated human pulmonary arteries (HPAs) when used at concentrations ranging from 1 to 30 µM. 1-Docosahexaenoyl-rac-glycerol also reduces ET-1-induced increases in HPA cell proliferation and VEGF levels.Formal Name: 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, 2,3-dihydroxypropyl ester. CAS Number: 140670-40-2. Synonyms: 1-Docosahexaenoin, MAG-DHA, MG(22:6/0:0/0:0). Molecular Formula: C25H38O4. Formula Weight: 402.6. Purity: >95% (mixture of isomers). Formulation: (Request formulation change), A solution in acetonitrile. Solubility: Acetonitrile: Soluble, Chloroform: Soluble. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OCC(O)CO)=O. InChi Code: InChI=1S/C25H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(28)29-23-24(27)22-26/h3-4,6-7,9-10,12-13,15-16,18-19,24,26-27H,2,5,8,11,14,17,20-23H2,1H3/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-. InChi Key: JWPHORDRFVRZPP-KUBAVDMBSA-N.