ZINC00881524

ZINC00881524 is a Rho-associated kinase (ROCK) inhibitor. It decreases levels of ROCK1 in T47D and CAMA-1 breast cancer cells. ZINC00881524 decreases proliferation of T47D and CAMA-1 cells when used in combination with CNN1 knockdown.Formal Name: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-3,4-dimethoxy-benzeneacetamide. CAS Number: 557782-81-7. Molecular Formula: C21H20N2O3S. Formula Weight: 380.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml. lambdamax: 232, 282 nm. SMILES: COC1=C(OC)C=CC(CC(NC2=NC(C(C=CC=C3)=C3CC4)=C4S2)=O)=C1. InChi Code: InChI=1S/C21H20N2O3S/c1-25-16-9-7-13(11-17(16)26-2)12-19(24)22-21-23-20-15-6-4-3-5-14(15)8-10-18(20)27-21/h3-7,9,11H,8,10,12H2,1-2H3,(H,22,23,24). InChi Key: DQNMDJGZWFZNHS-UHFFFAOYSA-N.