Zeaxanthin

Zeaxanthin is a dietary carotenoid that has been found in orange and yellow fruits and has diverse biological activities. In vivo, zeaxanthin (50 mg/kg) decreases immobility time in the forced swim test and reduces hippocampal levels of IL-6, IL-1beta, and TNF-alpha in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104). It also reduces albuminuria, serum levels of urea nitrogen and malondialdehyde (MDA), and kidney damage in a rat model of STZ-induced diabetic nephropathy. It forms the macular pigment in human eyes, and high dietary intake of zeaxanthin is positively correlated with reduced risk of advanced neovascular age-related macular degeneration in humans.Formal Name: beta,beta-carotene-3R,3'R-diol. CAS Number: 144-68-3. Synonyms: Anchovyxanthin, Xanthophyll 3, Zeaxanthol. Molecular Formula: C40H56O2. Formula Weight: 568.9. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble. lambdamax: 275, 452, 479 nm. SMILES: O[C@H]1CC(C)(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O)CC2(C)C)=C(C)C1. InChi Code: InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-24,35-36,41-42H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36-/. InChi Key: JKQXZKUSFCKOGQ-QAYBQHTQSA-N.