Z-IETD-AFC

Description: Z-IETD-AFC is a fluorescent substrate for caspase-8 and granzyme B. It can be used to quantify cysteinyl aspartate-8 or granzyme B activity. Smiles: CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F. References: Boudard D, et al. Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication. Leukemia. 2002,16(11):2343-2345.