(Z-Ala-Ala-Ala-Ala)2Rh110

(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.Formal Name: 4,4'-(3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl)bis[N-[(phenylmethoxy)carbonyl]-L-alanyl-L-alanyl-L-alanyl-L-alaninamide. CAS Number: 149695-85-2. Synonyms: (Z-Ala-Ala-Ala-Ala)2Rhodamine110, bis-(CBZ-L-alanyl-L-arginine amide) Rhodamine 110. Molecular Formula: C60H66N10O15. Formula Weight: 1167.2. Purity: >95%. Emission: 525 nm. Excitation: 485 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml, DMSO: 2 mg/ml. lambdamax: 229, 234, 285 nm. SMILES: O=C(NC1=CC(OC2=C3C=CC(NC([C@H](C)NC([C@H](C)NC([C@H](C)NC([C@H](C)NC(OCC4=CC=CC=C4)=O)=O)=O)=O)=O)=C2)=C(C35OC(C6=C5C=CC=C6)=O)C=C1)[C@H](C)NC([C@H](C)NC([C@H](C)NC([C@H](C)NC(OCC7=CC=CC=C7)=O)=O)=O)=O. InChi Code: InChI=1S/C60H66N10O15/c1-31(61-49(71)33(3)63-53(75)37(7)67-58(80)82-29-39-17-11-9-12-18-39)51(73)65-35(5)55(77)69-41-23-25-45-47(27-41)84-48-28-42(24-26-46(48)60(45)44-22-16-15-21-43(44)57(79)85-60)70-56(78)36(6)66-52(74)32(2)62-50(72)34(4)64-54(76)38(8)68-59(81)83-30-40-19-13-10-14-20-40/h9-28,31-38H,29-30H2,1-8H3,(H,61,71)(H,62,72)(H,63,75)(H,64,76)(H,65,73)(H,66,74)(H,67,80)(H,68,81)(H,69,77)(H,70,78)/t31-,32-,33-,34-,35-,36-,37-,38-/m0/s1. InChi Key: JGBISHWUFSPAPR-QSVFAHTRSA-N.