Wogonin

Anti-inflammatory. Increases nitric oxide (NO) production - Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS, NOS II) - Antioxidant - Anti-viral. Shows anti-hepatitis B virus activity - MCP-1 inhibitor - Shows anxiolytic effect through modulation of the GABA(A) receptor complex - Antifungal - Neuroprotective - Anticancer compound. Apoptosis and cell cycle arrest inducer - Sensitizes TNFalpha- and TRAIL-induced apoptosis - Antiangiogenic - NF-kappaB inhibitor - Telomerase activity inhibitor - CDK9 inhibitor - PI3K-AKT pathway modulator - Autophagy inducer