Verinurad

Verinurad is an inhibitor of urate anion transporter 1 (URAT1, IC50 = 0.025 µM for the human transporter). It is selective for human URAT1 over rat URAT1 (IC50 = 41 µM), as well as human organic anion transporter 1 (OAT1) and OAT4 (IC50s = 4.6 and 5.9 µM, respectively).Formal Name: 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl-propanoic acid. CAS Number: 1352792-74-5. Molecular Formula: C20H16N2O2S. Formula Weight: 348.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml. SMILES: OC(C(C)(C)SC1=CC=NC=C1C2=CC=C(C#N)C3=C2C=CC=C3)=O. InChi Code: InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24). InChi Key: YYBOLPLTQDKXPM-UHFFFAOYSA-N.