Velaresol

Velaresol is an oxyhemoglobin (Hb-O2) stabilizer. It increases erythrocyte deformability in isolated human blood from a patient with sickle cell disease when used at a concentration of 1.5 mM. Velaresol (3 or 5 mM) inhibits deoxygenation-induced decreases in erythrocyte deformability in isolated human blood from a patient with sickle cell disease. It decreases oxygen tension and increases oxygen saturation of isolated human sickle erythrocytes when used at a concentration of 5 mM.Formal Name: 5-(2-formyl-3-hydroxyphenoxy)-pentanoic acid. CAS Number: 77858-21-0. Synonyms: BW 12C, BW 12C79. Molecular Formula: C12H14O5. Formula Weight: 238.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 16 mg/mL, DMSO: 10 mg/mL, Ethanol: Slightly soluble. SMILES: O=CC1=C(OCCCCC(O)=O)C=CC=C1O. InChi Code: InChI=1S/C12H14O5/c13-8-9-10(14)4-3-5-11(9)17-7-2-1-6-12(15)16/h3-5,8,14H,1-2,6-7H2,(H,15,16). InChi Key: NSUDGNLOXMLAEB-UHFFFAOYSA-N.