VBIT-12

VBIT-12 is a voltage-dependent anion channel 1 (VDAC1) inhibitor. It inhibits VDAC1 conductance in synthetic lipid membranes containing purified rat VDAC1 when used at concentrations ranging from 20 to 100 µM.Formal Name: N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-glycine. CAS Number: 2089227-65-4. Molecular Formula: C25H27N3O3. Formula Weight: 417.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml, Ethanol: 15 mg/ml. lambdamax: 224 nm. SMILES: O=C(CNC(C1(CCN(CC1)CC2=CC=CC3=C2C=CC=C3)NC4=CC=CC=C4)=O)O. InChi Code: InChI=1S/C25H27N3O3/c29-23(30)17-26-24(31)25(27-21-10-2-1-3-11-21)13-15-28(16-14-25)18-20-9-6-8-19-7-4-5-12-22(19)20/h1-12,27H,13-18H2,(H,26,31)(H,29,30). InChi Key: JZDHWOWCHGYSGA-UHFFFAOYSA-N.