Varenicline-d4

Varenicline-d4 is intended for use as an internal standard for the quantification of varenicline (Cay-15030) by GC- or LC-MS. Varenicline is a full agonist of alpha7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs, EC50 = 18 µM) and a partial agonist of alpha4beta2 subunit-containing nAChRs (EC50 = 2.3 µM). Formulations containing varenicline have been used as aids in smoking cessation.Formal Name: 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-7,7,9,9-d4. CAS Number: 2183239-01-0. Molecular Formula: C13H9D4N3. Formula Weight: 215.3. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: Water: 0.0877 mg/mL. SMILES: [2H]C1([2H])NC([2H])([2H])C2C3=CC4=C(N=CC=N4)C=C3C1C2. InChi Code: InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2/i6D2,7D2. InChi Key: JQSHBVHOMNKWFT-KXGHAPEVSA-N.