USP8-IN-2

USP8-IN-2 is an inhibitor of ubiquitin-specific protease 8 (USP8, IC50 = 6 µM).Formal Name: N-(5-chloro-2-methoxyphenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-thiourea. CAS Number: 2477651-11-7. Synonyms: Ubiquitin-specific Protease 8-IN-2, Ubiquitin-specific Protease 8 Inhibitor 2, USP Inhibitor 2. Molecular Formula: C19H20ClF3N4OS. Formula Weight: 444.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml. SMILES: COC1=CC=C(C=C1NC(NC2CCN(C3=CC=CC(C(F)(F)F)=N3)CC2)=S)Cl. InChi Code: InChI=1S/C19H20ClF3N4OS/c1-28-15-6-5-12(20)11-14(15)25-18(29)24-13-7-9-27(10-8-13)17-4-2-3-16(26-17)19(21,22)23/h2-6,11,13H,7-10H2,1H3,(H2,24,25,29). InChi Key: XKLBIJSKEVHKCM-UHFFFAOYSA-N.