Tyramine-d4 (hydrochloride)

Tyramine-d4 is intended for use as an internal standard for the quantification of tyramine (Cay-18601) by GC- or LC-MS. Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist. It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively). Tyramine also inhibits the release of norepinephrine and dopamine in isolated rat caudate nucleus (IC50s = 40.6 and 119 nM, respectively).Formal Name: 4-(2-aminoethyl-1,1,2,2-d4)-phenol, monohydrochloride. CAS Number: 1189884-47-6. Synonyms: 2-(4-Hydroxyphenyl)ethylamine-d4, p-Tyramine-d4, Uteramine-d4. Molecular Formula: C8H7D4NO . HCl. Formula Weight: 177.7. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble, Water: slightly soluble. SMILES: OC1=CC=C(C([2H])([2H])C([2H])([2H])N)C=C1.Cl. InChi Code: InChI=1S/C8H11NO.ClH/c9-6-5-7-1-3-8(10)4-2-7,/h1-4,10H,5-6,9H2,1H/i5D2,6D2,. InChi Key: RNISDHSYKZAWOK-NXMSQKFDSA-N. Origin: Synthetic.