TMN 355

TMN 355 is an inhibitor of cyclophilin A (IC50 = 1.52 nM). It inhibits HIV-1 pseudoparticle infection of HEK293/T-17 cells when used at concentrations ranging from 0.1 to 1 µM.Formal Name: 2-chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluoro-benzamide. CAS Number: 1186372-20-2. Molecular Formula: C21H14ClFN2O2. Formula Weight: 380.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 40 mM. SMILES: O=C(NC(C1=C(F)C=CC=C1Cl)=O)NC2C(C=CC=C3)=C3C4=C2C=CC=C4. InChi Code: InChI=1S/C21H14ClFN2O2/c22-16-10-5-11-17(23)18(16)20(26)25-21(27)24-19-14-8-3-1-6-12(14)13-7-2-4-9-15(13)19/h1-11,19H,(H2,24,25,26,27). InChi Key: SFNLLCUAISZNRV-UHFFFAOYSA-N.