Tigilanol tiglate

Description: Tigilanol tiglate is a phorbol ester and acts as a protein kinase C regulator along with other related compounds. Target: Others. Smiles: O(C([C@H](CC)C)=O)[C@@]12[C@@](C1(C)C)([C@@]3([C@]4([C@](CO)(O4)[C@@H](O)[C@@]5(O)[C@]([C@@]3(O)[C@H](C)[C@H]2OC(/C(=C/C)/C)=O)(C=C(C)C5=O)[H])[H])[H])[H]. References: Boyle GM, D'Souza MM, Pierce CJ, Adams RA, Cantor AS, Johns JP, Maslovskaya L, Gordon VA, Reddell PW, Parsons PG. Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models. PLoS One. 2014 Oct 1,9(10):e108887. doi: 10.1371/journal.pone.0108887. eCollection 2014. PubMed PMID: 25272271, PubMed Central PMCID: PMC4182759.