Theophylline

Description: Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac, and central nervous system stimulant activities. It inhibits the 3', 5'-cyclic nucleotide phosphodiesterase that degrades cyclic AMP, thus potentiating the actions of agents that act through adenylyl cyclases and cyclic AMP. Target: Endogenous Metabolite, HDAC, Adenosine Receptor, Autophagy, PDE. Smiles: CN1C2=C(NC=N2)C(=O)N(C)C1=O. References: Philipp S, et al. Cardiovasc Res. 2006 May 1,70(2):308-14.