Tetrahydrozoline (hydrochloride)

Tetrahydrozoline is an alpha1-adrenergic receptor (alpha1-AR) agonist. Topical application to the eyes or nasal mucosa activates alpha1-ARs and induces vasoconstriction in rats, while oral administration activates central alpha2-ARs resulting in respiratory depression and hypotension in rats and rabbits. Formulations containing tetrahydrozoline have been used to treat eye irritation and nasal congestion.Formal Name: 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole, monohydrochloride. CAS Number: 522-48-5. Synonyms: Tetryzoline. Molecular Formula: C13H16N2 . HCl. Formula Weight: 236.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 25 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: C1(C=CC=C2)=C2C(C3=NCCN3)CCC1.Cl. InChi Code: InChI=1S/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13,/h1-2,4,6,12H,3,5,7-9H2,(H,14,15),1H. InChi Key: BJORNXNYWNIWEY-UHFFFAOYSA-N.