Tannic Acid

Tannic Acid
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay21421-5 5 g -

6 - 10 Werktage*

30,00 €
Cay21421-10 10 g -

6 - 10 Werktage*

46,00 €
Cay21421-25 25 g -

6 - 10 Werktage*

81,00 €
 
Tannic acid is a polyphenol of gallic acid (Cay-11846) that has been found in various plants and... mehr
Produktinformationen "Tannic Acid"
Tannic acid is a polyphenol of gallic acid (Cay-11846) that has been found in various plants and has antioxidant, anti-inflammatory, antiviral, and antiproliferative biological activities. Tannic acid (1 µM) inhibits the intracellular production of reactive oxygen species (ROS) and DNA damage induced by phorbol 12-myristate 13-acetate (TPA, Cay-10008014) in human polymorphonuclear neutrophils (PMNs). It also decreases TPA-induced nitric oxide release by 90% from primary rat hepatocytes when used at a concentration of 0.5 mM. Tannic acid inhibits hepatitis C virus (HCV) entry into Huh7.5 human hepatoma cells (IC50 = 5.8 µM) and inhibits the proliferation of MDA-MB-231 and MCF-7 human breast cancer cells (IC50s = 2.5 and 4 µM, respectively). In a rat model of middle cerebral artery occlusion (MCAO), it increases superoxide dismutase (SOD1) protein levels and decreases the amount of proteins modified by malondialdehyde (MDA) in ischemic brain tissue when administered at a dose of 10 mg/kg.Formal Name: 1,2,3,4,6-pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]beta-D-glucopyranose. CAS Number: 1401-55-4. Synonyms: Gallotannin. Molecular Formula: C76H52O46. Formula Weight: 1701.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 0.3 mg/ml. lambdamax: 219, 278 nm. SMILES: OC1=C(O)C(O)=CC(C(OC2=CC(C(OC[C@@H]3[C@@H](OC(C4=CC(O)=C(O)C(OC(C5=CC(O)=C(O)C(O)=C5)=O)=C4)=O)[C@H](OC(C6=CC(O)=C(O)C(OC(C7=CC(O)=C(O)C(O)=C7)=O)=C6)=O)[C@@H](OC(C8=CC(O)=C(O)C(OC(C9=CC(O)=C(O)C(O)=C9)=O)=C8)=O)[C@H](OC(C%10=CC(O)=C(O)C(OC(C%11=CC(O)=C(O)C(O)=C%11)=O)=C%10)=O)O3)=O)=CC(O)=C2O)=O)=C1. InChi Code: InChI=1S/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1. InChi Key: LRBQNJMCXXYXIU-PPKXGCFTSA-N.
Schlagworte: Tannic Acid, 1,2,3,4,6-pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]beta-D-glucopyranose
Hersteller: Cayman Chemical
Hersteller-Nr: 21421

Eigenschaften

Anwendung: Antioxidant, antiinflammatory, antiviral, antiproliferative polyphenol
MW: 1701.2 D
Formel: C76H52O46
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 1401-55-4| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H319, H402, H412
P-Sätze: P264, P273, P280, P305+351+338, P337+313, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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