SU3327

Description: SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 µM). Target: JNK. Smiles: Nc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1. References: De SK, et al. Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase. J Med Chem. 2009 Apr 9,52(7):1943-52.