STD1T

STD1T is an inhibitor of ubiquitin-specific protease 2a (USP2a, IC50 = 3.3 µM). It is selective for USP2a over USP7 at 10 µM. STD1T (20 µM) decreases cyclin D1 protein levels in HCT116 colon and MCF-7 breast cancer cells.Formal Name: 4,5,6,7-tetrahydro-2-[[2-[[5-(2-thienyl)-3-isoxazolyl]methoxy]acetyl]amino]-benzo[b]thiophene-3-carboxamide. CAS Number: 893075-58-6. Molecular Formula: C19H19N3O4S2. Formula Weight: 417.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMSO: 16 mg/ml. lambdamax: 225, 256, 262, 292 nm. SMILES: O=C(C1=C(NC(COCC2=NOC(C3=CC=CS3)=C2)=O)SC4=C1CCCC4)N. InChi Code: InChI=1S/C19H19N3O4S2/c20-18(24)17-12-4-1-2-5-14(12)28-19(17)21-16(23)10-25-9-11-8-13(26-22-11)15-6-3-7-27-15/h3,6-8H,1-2,4-5,9-10H2,(H2,20,24)(H,21,23). InChi Key: NRPUXFKWYPJDFT-UHFFFAOYSA-N.