Sp-Cyclic AMPS (sodium salt)

Description: Sp-cAMPS sodium salt is an analog of cAMP that serves as a potent activator of cAMP-dependent PKA I and PKA II, and as a competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 µM. It also binds the PDE10 GAF domain with an EC50 of 40 µM [1] [2] [3]. Target: Others. Smiles: O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP([S-])(OC2)=O)N3C4=NC=NC(N)=C4N=C3.[Na+]