SKQ1 (bromide)

SKQ1 (bromide) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer's disease, as well as decreases severity of arthritic lesions in rats. SKQ1 slows development of age-related ocular pathologies in murine, porcine, bovine, and canine model systems. It also prevents acute phenoptosis following rhabdomyolysis, stroke, and myocardial infarction.Formal Name: [10-(4,5-dimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium, monobromide. CAS Number: 934826-68-3. Molecular Formula: C36H42O2P . Br. Formula Weight: 617.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol and water (1:1). Solubility: Ethanol: Soluble. lambdamax: 225, 261 nm. SMILES: O=C(C(C)=C1C)C(CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=CC1=O.[Br-]. InChi Code: InChI=1S/C36H42O2P.BrH/c1-29-30(2)36(38)31(28-35(29)37)20-12-7-5-3-4-6-8-19-27-39(32-21-13-9-14-22-32,33-23-15-10-16-24-33)34-25-17-11-18-26-34,/h9-11,13-18,21-26,28H,3-8,12,19-20,27H2,1-2H3,1H/q+1,/p-1. InChi Key: WYHFWTRUGAFNKW-UHFFFAOYSA-M.