Sinensetin

Sinensetin is a polymethoxylated flavone that is present in the Southeast Asian medical plant O. stamineus, as well as in orange oil. It has been shown to enhance adipogenesis and lipolysis by increasing cAMP levels in 3T3-L1 cells. Sinensetin is also reported to inhibit alpha-glucosidase and alpha-amylase activity in vitro, indicating its potential usefulness in the control of glucose absorption. Additionally, sinensetin has been shown to suppress the expression of genes associated with inflammation by regulating IkappaBalpha protein levels in LPS-activated macrophages.Formal Name: 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one. CAS Number: 2306-27-6. Synonyms: Pedalitin Permethyl ether. Molecular Formula: C20H20O7. Formula Weight: 372.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/mL. lambdamax: 215, 241, 327 nm. SMILES: O=C1C2=C(OC)C(OC)=C(OC)C=C2OC(C3=CC=C(OC)C(OC)=C3)=C1. InChi Code: InChI=1S/C20H20O7/c1-22-13-7-6-11(8-15(13)23-2)14-9-12(21)18-16(27-14)10-17(24-3)19(25-4)20(18)26-5/h6-10H,1-5H3. InChi Key: LKMNXYDUQXAUCZ-UHFFFAOYSA-N.