Silodosin

Silodosin is a potent alpha1A-adrenoceptor antagonist (Ki = 0.036 nM). It shows selectivity for the prostatic adrenoceptor. As a result, it is effective against lower urinary tract symptoms associated with benign prostatic hyperplasia.Formal Name: 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide. CAS Number: 160970-54-7. Synonyms: KMD-3213. Molecular Formula: C25H32F3N3O4. Formula Weight: 495.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 25 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 269, 311 nm. SMILES: OCCCN(CC1)C(C1=C2)=C(C(N)=O)C=C2C[C@@H](C)NCCOC3=C(OCC(F)(F)F)C=CC=C3. InChi Code: InChI=1S/C25H32F3N3O4/c1-17(30-8-12-34-21-5-2-3-6-22(21)35-16-25(26,27)28)13-18-14-19-7-10-31(9-4-11-32)23(19)20(15-18)24(29)33/h2-3,5-6,14-15,17,30,32H,4,7-13,16H2,1H3,(H2,29,33)/t17-/m1/s1. InChi Key: PNCPYILNMDWPEY-QGZVFWFLSA-N.