Sesamol

Sesamol is a lignan originally isolated from S. indicum that has diverse biological activities, including antioxidant, antibacterial, anticancer, and anti-obesity properties. Sesamol scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) radicals with an IC50 value of 5.44 µg/ml and is active against B. cereus and S. aureus (MICs = 2 mg/ml for both). It also inhibits the growth of HepG2 human hepatocellular carcinoma cells in a concentration-dependent manner. Sesamol (100 mg/kg) reduces weight gain and hepatic steatosis in a mouse model of obesity induced by a high-fat diet (HFD).Formal Name: 1,3-benzodioxol-5-ol. CAS Number: 533-31-3. Synonyms: NSC 59256. Molecular Formula: C7H6O3. Formula Weight: 138.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: OC1=CC=C2OCOC2=C1. InChi Code: InChI=1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2. InChi Key: LUSZGTFNYDARNI-UHFFFAOYSA-N. Origin: Synthetic.