Sergliflozin A

Description: Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia. Target: SGLT. Smiles: O(C1=C(CC2=CC=C(OC)C=C2)C=CC=C1)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O. References: Pajor AM, et al. Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters. J Pharmacol Exp Ther. 2008 Mar,324(3):985-91.