Seco Rapamycin sodium salt

Description: Seco Rapamycin sodium salt is a ring-opened product of Rapamycin. Target: Others. Smiles: [Na].CO[C@@H](C[C@@H]1CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@H]1C(O)=O)C(\C)=C\C=C\C=C\[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(\C)=C\[C@@H](C)C(=O)\C=C\[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC. References: Paine MF, et al. Identification of a novel route of extraction of sirolimus in human small intestine: roles ofmetabolism and secretion. J Pharmacol Exp Ther. 2002 Apr,301(1):174-86.