SD 2590 (hydrochloride)

SD 2590 is an inhibitor of matrix metalloproteinase-2 (MMP-2), -3, -8, -9, and -13 (IC50s = 50s = >10,000 and 7,000 nM, respectively). SD 2590 (10 mg/kg per day) inhibits dilation of the left ventricle in rats following myocardial infarction (MI) compared to MI vehicle control animals.Formal Name: N-hydroxy-1-(2-methoxyethyl)-4-[[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide, monohydrochloride. CAS Number: 226395-93-3. Synonyms: SC-78080. Molecular Formula: C22H25F3N2O7S . HCl. Formula Weight: 555.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM, Water: 100 mM. SMILES: FC(F)(F)OC1=CC=C(OC2=CC=C(S(C3(C(NO)=O)CCN(CCOC)CC3)(=O)=O)C=C2)C=C1.Cl. InChi Code: InChI=1S/C22H25F3N2O7S.ClH/c1-32-15-14-27-12-10-21(11-13-27,20(28)26-29)35(30,31)19-8-6-17(7-9-19)33-16-2-4-18(5-3-16)34-22(23,24)25,/h2-9,29H,10-15H2,1H3,(H,26,28),1H. InChi Key: HJJOIVGDTLHVTK-UHFFFAOYSA-N.