Scopolamine N-butyl (bromide)

Scopolamine N-butyl is an antispasmodic agent. In vivo, scopolamine N-butyl inhibits electrically induced urinary bladder contractions in dogs (ED50s = 0.07-4.7 mg/kg). It also decreases the ileal phasic motility index (PMI) as well as colonic motility in canine models of ileal and colonic fistulas, respectively. Formulations containing scopolamine N-butyl have been used in the treatment of pain induced by abdominal cramps and bladder spasms.Formal Name: (1alpha,2beta,4beta,5alpha,7beta)-9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, monobromide. CAS Number: 149-64-4. Synonyms: Hyoscine butobromide, N-butyl Hyoscine. Molecular Formula: C21H30NO4 . Br. Formula Weight: 440.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 3mg/mL, DMSO: 5mg/mL, Ethanol: 2.5mg/mL, PBS (pH 7.2): 10mg/mL. lambdamax: 273 nm. SMILES: O=C(O[C@@H]1C[C@@H]([N@+]2(CCCC)C)[C@H]3O[C@H]3[C@@H]2C1)[C@H](CO)C4=CC=CC=C4.[Br-]. InChi Code: InChI=1S/C21H30NO4.BrH/c1-3-4-10-22(2)17-11-15(12-18(22)20-19(17)26-20)25-21(24)16(13-23)14-8-6-5-7-9-14,/h5-9,15-20,23H,3-4,10-13H2,1-2H3,1H/q+1,/p-1/t15-,16-,17-,18+,19-,20+,22-,/m1./s1. InChi Key: HOZOZZFCZRXYEK-UBNOCOESSA-M.