Sartorypyrone B

Description: Sartorypyrone B, a 2beta-acetoxyl analogue of chevalone C, is derived from the ethyl acetate extract of the culture of Neosartorya tsunodae (KUFC 9213), a fungus associated with marine sponges. This compound demonstrates potent growth inhibitory activity against MCF-7, NCI-H460, and A375-C5 cancer cell lines with GI50 values of 17.8, 20.5, and 25.0 µM, respectively, indicating its potential in the study of breast adenocarcinoma, non-small cell lung cancer, and melanoma [1]. Smiles: [H][C@@]12CC[C@]3(C)[C@]([H])(CC[C@]4(C)Oc5oc(C)cc(=O)c5C[C@@]34[H])[C@@]1(C)C[C@H](OC(C)=O)[C@H](OC(C)=O)C2(C)C