Sartorypyrone B

Sartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity. It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 µM, respectively).Formal Name: (2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-rel-(-)-2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one. CAS Number: 1452396-11-0. Molecular Formula: C30H42O7. Formula Weight: 514.7. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: CC(OC1=C2C[C@]3([H])[C@@](CC[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)C[C@H](OC(C)=O)[C@H](OC(C)=O)C5(C)C)(C)O1)=CC2=O. InChi Code: InChI=1S/C30H42O7/c1-16-13-20(33)19-14-24-28(6)11-9-22-27(4,5)25(36-18(3)32)21(35-17(2)31)15-29(22,7)23(28)10-12-30(24,8)37-26(19)34-16/h13,21-25H,9-12,14-15H2,1-8H3/t21-,22-,23-,24-,25-,28+,29-,30-/m0/s1. InChi Key: DFAVZYUGRTVMCA-KNUPVKMWSA-N. Origin: Fungus/Neosartorya sp..