Saroglitazar Magnesium

Description: Saroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARalpha (EC50 0.65pM) and moderate activation against PPARgamma (EC50 3 nM). Target: Others. Smiles: C(C)O1[Mg+2]2(O(CC)C(CC3=CC=C(OCCN4C(=CC=C4C)C5=CC=C(SC)C=C5)C=C3)C(=O)[O-]2)[O-]C(=O)C1CC6=CC=C(OCCN7C(=CC=C7C)C8=CC=C(SC)C=C8)C=C6. References: Jain MR, et al. Saroglitazar, a novel PPARalpha/gamma agonist with predominant PPARalpha activity, shows lipid-lowering and insulin-sensitizing effects in preclinical models. Pharmacol Res Perspect. 2015 Jun,3(3):e00136.