Salvianolic Acid B

Salvianolic acid B is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties. It has been reported to reduce leukocyte-endothelial adherence, inhibit inflammation and metalloproteinase expression from aortic smooth muscle cells, and regulate immune function and certain intracellular kinase associated signaling pathways by competitively inhibiting the protein-protein interactions mediated by key binding domains.Formal Name: 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid (2S,3S)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester. CAS Number: 121521-90-2. Synonyms: Lithospermate B. Molecular Formula: C36H30O16. Formula Weight: 718.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: OC1=CC=C(C[C@H](C(O)=O)OC(/C=C/C2=CC=C(O)C3=C2[C@H](C(O[C@@H](C(O)=O)CC4=CC(O)=C(O)C=C4)=O)[C@@H](C5=CC(O)=C(O)C=C5)O3)=O)C=C1O. InChi Code: InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,2. InChi Key: SNKFFCBZYFGCQN-VWUOOIFGSA-N. Origin: Plant/Salviae Miltiorrhizae Radix et Rhizoma.