(S)-Laudanosine

(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium (Cay-17796) and cisatracurium (Cay-22959). (S)-Laudanosine is also an alkaloid that has been found in the prickly poppy A. platyceras. It inhibits prolyl endopeptidase with an IC50 value of 341 µM. (S)-Laudanosine (100 µM) inhibits both arachidonic acid- and collagen-induced aggregation in washed rabbit platelets.Formal Name: (1S)-1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline. CAS Number: 2688-77-9. Synonyms: (+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045. Molecular Formula: C21H27NO4. Formula Weight: 357.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Ethanol: slightly soluble, Methanol: slightly soluble. SMILES: COC1=C(OC)C=C(CCN(C)[C@H]2CC3=CC=C(OC)C(OC)=C3)C2=C1. InChi Code: InChI=1S/C21H27NO4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17H,8-10H2,1-5H3/t17-/m0/s1. InChi Key: KGPAYJZAMGEDIQ-KRWDZBQOSA-N. Origin: Synthetic.