(S)-(-)-BAY-K-8644

(S)-(-)-BAY-K-8644 is an activator of voltage-sensitive L-type calcium channels. It demonstrates vasoconstrictive and positive inotropic effects in vivo as well as behavioral effects, including deficits to motor function. When combined with BIX01294 (Cay-13124), (S)-(-)-BAY-K-8644 can enable reprogramming of mouse embryonic fibroblasts after transduction with Oct4/Klf4.Formal Name: (4S)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester. CAS Number: 98625-26-4. Molecular Formula: C16H15F3N2O4. Formula Weight: 356.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2) (1:9): 0.1 mg/ml. lambdamax: 236, 272, 404 nm. SMILES: O=C(OC)C1=C(C)NC(C)=C([N+]([O-])=O)[C@H]1C2=CC=CC=C2C(F)(F)F. InChi Code: InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1. InChi Key: ZFLWDHHVRRZMEI-ZDUSSCGKSA-N.